Abscess - Causes 

Causes of an abscess 

Most abscesses are caused by a bacterial infection.

Bacteria

When bacteria enter your body, your immune system tries to fight the infection by sending white blood cells to the affected area. The white blood cells (polymorphs) kill them and then die. As the white blood cells attack the bacteria, inflammation (swelling) and death of nearby tissue may occur, causing a hollow to form.

The hollow fills with pus to form the abscess. The pus contains a mixture of dead tissue, white blood cells and bacteria. The abscess may get larger and more painful as the infection continues and more pus is produced.

Staphylococcus aureus and streptococci are the most common types of bacteria that cause skin abscesses on the following areas of the body:

  • head and neck
  • limbs
  • underarms
  • torso

See the Health A-Z topic about Staphylococcal infections for more information.

PVL Staphylococcus aureus

Staphylococcus aureus is a type of bacterium found on the surface of healthy skin. It can cause skin infections, such as skin abscesses and boils, and prefers to live in moist areas of the body such as:

  • the armpits
  • the groin
  • inside the nostrils

Some S. aureus bacteria can produce a poisonous substance called Panton-Valentine leukocidin (PVL), which kills the white cells, causing the body to make more white cells to continue to fight the infection.

PVL-positive strains of bacteria are therefore more likely to cause skin infections and abscesses. They can also cause more serious conditions:

  • Septicaemia is blood poisoning caused by bacteria multiplying in the blood. 
  • Pneumonia is swelling (inflammation) of the lungs caused by an infection. Pus collects in the airways and is coughed up as mucus.

Skin abscesses

Bacteria can cause a skin abscess when they get under the surface of your skin. An abscess may occur if you have a minor skin wound, such as a small cut or graze, or if a sebaceous gland (oil gland) or a sweat gland in your skin becomes blocked.

Boils occur as the result of bacteria entering the root of a hair on your skin.

In most cases, skin abscesses are not a sign of an underlying health problem. However, you are more likely to develop a skin abscess if you have diabetes. Diabetes can cause nerve damage, which can mean you are unable to feel any minor cuts and grazes to your skin.

Meticillin-resistant Staphylococcus aureus (MRSA) has been a common cause of skin abscesses in recent years.

See the Health A-Z topic about MRSA infection for more information.

Internal abscesses

Abscesses that occur in the abdomen (tummy) can be caused by:

  • an infection
  • a tear (rupture) of the intestine
  • an injury
  • surgery to the abdomen

An abscess can occur inside your body when bacteria spread from an existing infection.

For example, a lung abscess can occur as a result of a bacterial infection that is already present in your lungs, such as pneumonia (inflammation of the lung tissue). Bacteria can also spread from other areas of your body through your bloodstream.

Internal abscesses tend to occur in people who have an underlying health problem, such as a brain abscess that develops after a severe head wound. Internal abscesses can also sometimes develop in people with damaged immune systems, such as those with HIV and AIDS or those who are having chemotherapy treatment for cancer.

Risk factors

Risk factors that are known to increase the likelihood of an abscess developing include:

  • trauma to a specific area of the body
  • a weakened immune system
  • any material getting into the body
  • a drainage system in the body becoming blocked
  • a build-up of fluid in the tissues of the body
  • a haematoma (collection of blood outside a blood vessel)

Last reviewed: 25/08/2010

Next review due: 25/08/2012

Comments are personal views. Any information they give has not been checked and may not be accurate.

LizH222 said on 15 March 2011

Yes indeed! I agree this should be on the NHS site. Do you get abscesses in your armpits/groin especially - never go away, if they do they soon come back ! Ask your gp to check this condition out. You can also log into the hidradenitis suppuprativa uk organization, just google the word. I suffered for 30 years with this (though my current gp does know about this cdt) - all the doctors & at the hospitals here in north west coast - treated them as boils - they cut them all the time - so painful when they did that, i would pass out, be sick etc and the nurses could never believe the amount that would come out once cut, it left me with permanent and awful scarring in groins and armpits. Do not let anyone cut them like a boil. Most doctors think they are and treat them so. Eventually I when i went to Aberdeen 10 years ago a doctor identified it - sent me to Aberdeen hospital and the operated & cut my armpit out (under anaesthetic ). They could not believe that the hospitals down here actually cut them & said it must have been like ‘torture’! It was. Lots of people seem to have this - yet a lot of gp's & hospitals don't know what it is !
Don't suffer in silence - check out the website.

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marshell said on 24 September 2009

No mention has been made here on a condition known as HIDRADENITIS SUPPURATIVA which I believe to be more common than is thought. This condition results in many abscess and is largely unknown to most Doctors. For anyone suffering from this condition, or anyone who has repeatedly suffered in this way go to www.ba-hs.org.uk/ for more information.

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